C-type lectin receptor信号通路
WebOct 1, 2015 · The C-type lectins are the largest and most diverse of the lectin families found in animals. C-type lectins contain an independently folding, modular carbohydrate-recognition domain (CRD) that in most cases binds sugars by ligation to Ca 2+, making the sugar-binding activity Ca 2+ -dependent [ 2]. Many receptors containing C-type CRDs … Web-20°C/1 year; 分子量: 24kD; 背景: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response.
C-type lectin receptor信号通路
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WebC-型凝集素(C-type Lectins)是一類可以和糖類結合的蛋白質。 它們區別於其他類型的 凝集素 是在於它們含有大約120個胺基酸序列的鈣依賴型的 糖類識別區域 (carbohydrate … WebProtein-carbohydrate interactions serve multiple functions in the immune system. Many animal lectins (sugar-binding proteins) mediate both pathogen recognition and cell-cell interactions using structurally related Ca(2+)-dependent carbohydrate-recognition domains (C-type CRDs).
WebC-type lectin receptor that binds carbohydrates mannose and fucose but also weakly interacts with N-acetylglucosamine (GlcNAc) in a Ca 2+-dependent manner (PubMed:27015765). Involved in regulating immune reactivity (PubMed:18258799, PubMed:10438934). Once triggered by antigen, it is internalized by clathrin-dependent …
WebJun 15, 2011 · The C-type lectins are one of the pattern recognition receptors (PRRs) with lectin-like carbohydrate recognition domains (CRDs) in their extracellular … WebJun 22, 2024 · Dectin-2 recognizes mannosylated lipoarabinomannan (ManLAM), dendritic cell immunoactivating receptor (DCAR) recognizes phosphatidylinositol mannosides …
WebCalcium-dependent lectin that acts as a pattern recognition receptor (PRR) of the innate immune system: recognizes damage-associated molecular patterns (DAMPs) of abnormal self and pathogen-associated molecular patterns (PAMPs) of bacteria and fungi (PubMed:18509109, PubMed:23602766). The PAMPs notably include mycobacterial …
WebFeb 18, 2024 · C-type lectin-like receptors (CLRs) represent a family of transmembrane pattern recognition receptors, expressed primarily by myeloid cells. They recognize not only pathogen moieties for host defense, but also modified self-antigens such as damage-associated molecular patterns released from dead cells. Upon ligation, CLR signaling … images of gmc suvsWebFeb 18, 2024 · C-type lectin-like receptors (CLRs) represent a family of transmembrane pattern recognition receptors, expressed primarily by myeloid cells. They recognize not … images of glowing tubes in amplifiersWeb1、对胰岛素和胰岛素样生长因子的响应. PI3K-AKT-mTOR是经典的响应胰岛素信号的通路。. 当进食后,被分解的葡萄糖进入血液促进胰岛素的释放,胰岛素作为响应营养富余的 … list of airlines in sri lankaWebOverview of RIG-I-like Receptors. The RIG-I-like receptors (RLRs) are a family of cytosolic pattern recognition receptors that are essential for detecting viral RNA and initiating the innate immune response. The RLR … list of airlines in australiaWebJun 13, 2016 · C-type lectin receptors (CLRs) are efficient pattern-recognition receptors (PRRs) that interact with pathogens via carbohydrate structures, leading to enhanced … list of airlines flying from jfkWebJul 9, 2024 · 对于细胞外病原微生物,包括Toll样受体(Toll-like receptors,TLRs)和C型凝集素受体(C-type lectin receptors,CLRs)在内的跨膜受体是主要的感受器 ,这些受体的信 … list of airlines in nepalWebC-type lectin receptors (CLRs) comprise a large family of receptors that bind to carbohydrates in a calcium-dependent manner. The lectin activity of these receptors is mediated by conserved carbohydrate-recognition … list of airlines in latin america