Dithiolane trimethylene carbonate
WebScheme 1 Illustration of doxorubicin-loaded ApoE peptide-functionalized reduction-sensitive polymersomes (ApoE-PS-DOX) for the delivery of DOX to orthotopic human U-87 glioblastoma xenografts in nude mice. ApoE-PS-DOX engineered with ApoE can boost its BBB penetration and cellular uptake via LRP-1-mediated mechanism. The reduction … WebJan 1, 2024 · Reduction-responsive core-crosslinked hyaluronic acid-b-poly(trimethylene carbonate- co -dithiolane trimethylene carbonate) micelles : Synthesis and CD44-mediated potent delivery of docetaxel to triple negative breast tumor in vivo: Published in: Journal of Materials Chemistry B, 6(19), 3040 - 3047. Royal Society of Chemistry. ISSN …
Dithiolane trimethylene carbonate
Did you know?
WebMay 6, 2015 · These materials exhibit self-healing behavior, can be injected through a … WebMelanoma is a malignant tumor arising in melanocytes from the basal layer of the epidermis and is the fifth most commonly diagnosed cancer in the United States. Melanoma is aggressive and easily metastasizes, and the survival rate is low. Nanotechnology-based diagnosis and treatment of melanoma have attracted increasing attention. Importantly, …
WebApr 10, 2024 · Future cancer therapy relies on the development of simple, selective and … WebScheme 1 Illustration of doxorubicin-loaded ApoE peptide-functionalized reduction-sensitive polymersomes (ApoE-PS-DOX) for the delivery of DOX to orthotopic human U-87 glioblastoma xenografts in nude mice. ApoE-PS-DOX engineered with ApoE can boost its BBB penetration and cellular uptake via LRP-1-mediated mechanism. The reduction …
Web开馆时间:周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 WebMay 7, 2024 · The ring opening copolymerization of trimethylene carbonate (TMC) and …
WebJul 31, 2024 · Zhong and co-workers reported the preparation of a self-cross-linking, reduction-responsive polymersome decorated with cRGD and fusogenic GALA peptide by the coassembly of the three triblock copolymers PEG-b-poly(trimethylene carbonate-co-dithiolane trimethylene carbonate)spermine (PEG-b-P(TMC-co-DTC)-spermine), …
WebJun 11, 2024 · The ring opening copolymerization of trimethylene carbonate (TMC) and … pisola 鈴鹿WebDec 28, 2024 · 1. Introduction. Glioblastoma with intracranial infiltrative growth remains an incurable disease. One of the reasons is the poor permeability of therapeutics through the blood brain barrier (BBB) [[1], [2], [3], [4]].In the past years, brain-targeting nanomedicines that are able to cross the BBB have been designed to enhance the chemotherapy for … pisoli talukaWebSep 1, 2024 · Section snippets Synthesis of PEG-P(TMC-DTC)-PAsp. PEG-P(TMC-DTC) block copolymer with an M n of 5.0 − 14.6–2.1 kg/mol and p-nitrophenyl chloroformate (NPC) activated copolymer PEG-P(TMC-DTC)-NPC were synthesized as previously reported [45].First, under nitrogen environment into a stirred solution of 4 mL anhydrous … pisolim