Webb9 dec. 2024 · A cell-free assay is used to systematically measure the off-rate of 13 different TCR/pMHC interactions under different applied forces. In contrast to studies using intact T cells, we found that applied force increased the off-rate of high-affinity TCR/pMHC interactions by more than it did for low-affinity interactions. WebbCALCRL:RAMP1-CRE-bla FreeStyle™ 293F cells are functionally validated for Z'-factor and EC50 concentrations of Alpha-CGRP. In addition, CALCRL:RAMP1-CRE-bla FreeStyle™ 293F cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and …
Robert L Ross - Sr Product Application Specialist
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Thermo Fisher releases upgrades to analytical software
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